Characterization of In Vitro 3D Cell Model Developed from Human Hepatocellular Carcinoma (HepG2) Cell Line

In genetic toxicology, there is a trend against the increased use of in vivo models as highlighted by the 3R strategy, thus encouraging the development and implementation of alternative models. Two-dimensional (2D) hepatic cell models, which are generally used for studying the adverse effects of che...

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Bibliographic Details

Published in:	Cells
Main Authors:	Martina Štampar, Barbara Breznik, Metka Filipič, Bojana Žegura
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Subjects:	3D cell model HepG2 cell proliferation cell cycle gene expression
Online Access:	https://www.mdpi.com/2073-4409/9/12/2557