Role of N-linked glycosylation sites in human ACE2 in SARS-CoV-2 and hCoV-NL63 infection

ABSTRACT Angiotensin-converting enzyme 2 (ACE2) is a transmembrane protein known for its physiological role in the renin-angiotensin system that also serves as a receptor for entry of SARS-CoV-1, SARS-CoV-2, and the seasonal human coronavirus NL63 (hCoV-NL63). ACE2 contains seven N-linked glycosylat...

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出版年:	Journal of Virology
主要な著者:	Sabrina Noettger, Fabian Zech, Rayhane Nchioua, Chiara Pastorio, Christoph Jung, Timo Jacob, Steffen Stenger, Frank Kirchhoff
フォーマット:	論文
言語:	英語
出版事項:	American Society for Microbiology 2025-05-01
主題:	SARS-CoVs hCoV-NL63 ACE2 glycosylation infection cell-to-cell fusion
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/jvi.02202-24