Advances in biomaterials for osteonecrosis treatment

Osteonecrosis, or ischemic osteonecrosis, occurs when bone tissue dies due to a reduced blood supply. This process begins with the death of osteocytes and is followed by the development of necrotic bone tissue. The body initiates intrinsic repair mechanisms to counteract osteonecrosis. However, insu...

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Bibliographic Details
Published in:Frontiers in Pharmacology
Main Authors: Dapeng Wang, Jiannan Li, Yu Liu, Shuaishuai Wang, Shuo Duan, Zhiyang Liu, Shuaiwei Li, Jun Liang, Guangwei Meng, Minglei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1559810/full