Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings

Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant...

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Bibliographic Details

Published in:	Pediatric Discovery
Main Authors:	Ethan S. Wong, Daniel A. Hu, Lily Zhang, Rachel Qi, Cindy Xu, Ou Mei, Guowei Shen, Wulin You, Changqi Luo, Tong‐Chuan He, Russell R. Reid, Lewis S. Shi, Michael J. Lee, Yi Zhu
Format:	Article
Language:	English
Published:	Wiley 2025-06-01
Subjects:	genetics neural tube defects risk factors spina bifida spinal dysraphism
Online Access:	https://doi.org/10.1002/pdi3.2517