A comparison of five different drug-drug interaction checkers for selective serotonin reuptake inhibitors

BackgroundSelective serotonin reuptake inhibitors (SSRIs) are widely prescribed for depression and anxiety, but their potential for drug-drug interactions (DDIs) poses significant risks, particularly given their influence on cytochrome P450 enzymes. Variability in identifying and classifying these i...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shanshan Xu, Zhihui Song, Yiman Li, Jie Bai, Dong Wang, Ente Wang, Jiawei Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	drug-drug interaction checkers selective serotonin reuptake inhibitors potential drug-drug interactions consistency evaluation clinical decision-making
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1690975/full