Efficacy and safety of simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative chemotherapy treatment of multifocal high-grade glioma

BackgroundThe multifocal manifestation of high-grade glioma is a rare disease with an unfavorable prognosis. The pathogenesis of multifocal gliomas and pathophysiological differences in unifocal gliomas are not fully understood. The optimal treatment for patients with multifocal high-grade glioma is...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Nan Jiang, Li-ping Xu, Fei Li, Pei-pei Wang, Yuandong Cao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	multifocal high-grade glioma simultaneous integrated boost intensity modulated radiotherapy temozolomide efficacy toxicity
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1539362/full