A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

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發表在:	eLife
Main Authors:	Bjoern Gaertner, Sebastiaan van Heesch, Valentin Schneider-Lunitz, Jana Felicitas Schulz, Franziska Witte, Susanne Blachut, Steven Nguyen, Regina Wong, Ileana Matta, Norbert Hübner, Maike Sander
格式:	Article
語言:	英语
出版:	eLife Sciences Publications Ltd 2020-08-01
主題:	lncRNA pancreas ORF detection endocrine development endoderm microproteins
在線閱讀:	https://elifesciences.org/articles/58659