Evaluating effect of metallic ions on aggregation behavior of β-amyloid peptides by atomic force microscope and surface-enhanced Raman Scattering

Abstract Background Excessive aggregation of β-amyloid peptides (Aβ) is regarded as the hallmark of Alzheimer’s disease. Exploring the underlying mechanism regulating Aβ aggregation remains challenging and investigating aggregation events of Aβ in the presence and absence of metallic ions at molecul...

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Bibliographic Details

Published in:	BioMedical Engineering OnLine
Main Authors:	Yang Xie, Lin Yu, Yuna Fu, Heng Sun, Jianhua Wang
Format:	Article
Language:	English
Published:	BMC 2021-12-01
Subjects:	β-Amyloid peptides Self-assembly monolayers Atomic force microscopy Surface-enhanced Raman Scattering
Online Access:	https://doi.org/10.1186/s12938-021-00972-7