CRISPR‐based gene therapy for wet age‐related macular degeneration in mouse model

Abstract Wet age‐related macular degeneration (AMD) is a common cause of vision loss in the elderly. It is characterised by choroidal neovascularisation (CNV), caused by overexpression of vascular endothelial growth factor (VEGF), resulting in abnormal vessel proliferation. Current clinical manageme...

Full description

Bibliographic Details

Published in:	Clinical and Translational Discovery
Main Authors:	Dongchun Xie, Yuxi Chen, Sihui Hu, Li Huang, Junjiu Huang
Format:	Article
Language:	English
Published:	Wiley 2024-02-01
Subjects:	CRISPR gene editing VEGF‐related pathway VEGFA wet AMD
Online Access:	https://doi.org/10.1002/ctd2.278