LGR5 Expression Predicting Poor Prognosis Is Negatively Correlated with WNT5A in Colon Cancer

WNT/β-catenin signaling is essential for colon cancer development and progression. WNT5A (ligand of non-canonical WNT signaling) and its mimicking peptide Foxy5 impair β-catenin signaling in colon cancer cells via unknown mechanisms. Therefore, we investigated whether and how WNT5A signaling affects...

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Bibliographic Details
Published in:Cells
Main Authors: Lubna M. Mehdawi, Souvik Ghatak, Payel Chakraborty, Anita Sjölander, Tommy Andersson
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Subjects:
WNT5A
Foxy5
LGR5
R-spondin3
WNT/β-catenin signaling
VEGFA
Online Access:https://www.mdpi.com/2073-4409/12/22/2658

Internet

https://www.mdpi.com/2073-4409/12/22/2658

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