Nitric oxide synthase and intermittent hypoxia-induced spatial learning deficits in the rat

Intermittent hypoxia (IH) during sleep induces significant neurobehavioral deficits in the rat. Since nitric oxide (NO) has been implicated in ischemia-reperfusion-related pathophysiological consequences, the temporal effects of IH (alternating 21% and 10% O2 every 90 s) and sustained hypoxia (SH; 1...

Full description

Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Richard C. Li, Barry W. Row, Leila Kheirandish, Kenneth R. Brittian, Evelyne Gozal, Shang Z. Guo, Leroy R. Sachleben, Jr, David Gozal
Format:	Article
Language:	English
Published:	Elsevier 2004-10-01
Subjects:	iNOS eNOS nNOS Intermittent hypoxia Neurobehavioral deficits Knockout mice
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996104001238