Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts

Among cells present in the tumor microenvironment, activated fibroblasts termed cancer-associated fibroblasts (CAFs), play a critical role in the complex process of tumor-stroma interaction. CAFs, one of the prominent stromal cell populations in most types of human carcinomas, have been involved in...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Linda Ziani, Salem Chouaib, Jerome Thiery
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-03-01
Subjects:	cancer tumor microenvironment cancer-associated fibroblasts immune suppression immunotherapy
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00414/full