Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

Abstract Background Muir‐Torre syndrome is defined by the development of sebaceous skin lesions in individuals who carry a germline mismatch repair (MMR) gene mutation. Loss of expression of MMR proteins is frequently observed in sebaceous skin lesions, but MMR‐deficiency alone is not diagnostic for...

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Bibliographic Details

Published in:	Molecular Genetics & Genomic Medicine
Main Authors:	Peter Georgeson, Michael D. Walsh, Mark Clendenning, Simin Daneshvar, Bernard J. Pope, Khalid Mahmood, Jihoon E. Joo, Harindra Jayasekara, Mark A. Jenkins, Ingrid M. Winship, Daniel D. Buchanan
Format:	Article
Language:	English
Published:	Wiley 2019-07-01
Subjects:	Lynch syndrome mismatch repair deficiency mismatch repair immunohistochemistry Muir‐Torre syndrome sebaceoma sebaceous adenoma
Online Access:	https://doi.org/10.1002/mgg3.781