Sex differences and the role of estrogens in the immunological underpinnings of Alzheimer's disease

Abstract Alzheimer's disease (AD) affects women more frequently and more severely than men, but the biological mechanisms underlying these sex differences remain poorly understood. This review integrates recent findings from neuroscience, immunology, endocrinology, and genetics to explore how s...

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Bibliographic Details

Published in:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Main Authors:	Brittani R. Price, Keenan A. Walker, Jaclyn M. Eissman, Vidyani Suryadevara, Lindsey N. Sime, Timothy J. Hohman, Marcia N. Gordon
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Subjects:	adaptive immunity apolipoprotein E astrocytes cognitive decline estradiol estrogen
Online Access:	https://doi.org/10.1002/trc2.70139