Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2

Smurf2, one of C2-WW-HECT domain E3 ubiquitin ligases, is closely related to the development and progression in different cancer types, including hepatocellular carcinoma (HCC). This study aims to illustrate the expression and molecular mechanism of Smurf2 in regulating the progression of HCC.

Bibliographic Details

Published in:	Open Medicine
Main Authors:	Song Dongqiang, Li Shuyu, Ning Liuxin, Zhang Shuncai, Cai Yu
Format:	Article
Language:	English
Published:	De Gruyter 2022-02-01
Subjects:	smurf2 hepatocellular carcinoma smad2 ubiquitination metastasis
Online Access:	https://doi.org/10.1515/med-2022-0437