CRISPR FokI Dead Cas9 System: Principles and Applications in Genome Engineering

The identification of the robust clustered regularly interspersed short palindromic repeats (CRISPR) associated endonuclease (Cas9) system gene-editing tool has opened up a wide range of potential therapeutic applications that were restricted by more complex tools, including zinc finger nucleases (Z...

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Bibliographic Details

Published in:	Cells
Main Authors:	Maryam Saifaldeen, Dana E. Al-Ansari, Dindial Ramotar, Mustapha Aouida
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Subjects:	genome engineering CRISPR dead Cas9 FokI endonuclease FokI-dCas9 RNA-guided FokI nuclease
Online Access:	https://www.mdpi.com/2073-4409/9/11/2518