Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction

Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at restoring the proper function of the ER. Prolonged activation of the UPR leads...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Aisha Osman, Tarek Benameur, Hesham M. Korashy, Asad Zeidan, Abdelali Agouni
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Subjects:	extracellular vesicles (EVs) microparticles (MPs) endoplasmic reticulum (ER) stress endothelial dysfunction cardiovascular disease diabetes
Online Access:	https://www.mdpi.com/2227-9059/8/10/409