Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3.

Aneuploidy typically poses challenges for cell survival and growth. However, recent studies have identified exceptions where aneuploidy is beneficial for cells with mutations in certain regulatory genes. Our research reveals that cells lacking the spindle checkpoint gene BUB3 exhibit aneuploidy of s...

詳細記述

書誌詳細
出版年:PLoS Genetics
主要な著者: Pallavi Gadgil, Olivia Ballew, Timothy J Sullivan, Soni Lacefield
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2025-02-01
オンライン・アクセス:https://doi.org/10.1371/journal.pgen.1011576