TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages: A proteomic and metabolomic insight

Titanium dioxide nanoparticles (TiO2 NPs) are widely used in food and cosmetics but the health impact of human exposure remains poorly defined. Emerging evidence suggests that TiO2 NPs may elicit immune responses by acting on macrophages. Our proteomic study showed that treatment of macrophages with...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Qun Chen, Ningning Wang, Mingjiang Zhu, Jianhong Lu, Huiqin Zhong, Xinli Xue, Shuoyuan Guo, Min Li, Xinben Wei, Yongzhen Tao, Huiyong Yin
Format:	Article
Language:	English
Published:	Elsevier 2018-05-01
Subjects:	TiO2 nanoparticles Macrophages Mitochondrial dysfunction Inflammation Proteomics Metabolomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231717306584