Investigating the role of the ALPK1 signaling pathway in the pathogenesis of diabetic retinopathy

Abstract Diabetic retinopathy (DR) is a key eye-related complication linked to diabetes. Chronic inflammation is recognized as the main pathological mechanism leading to retinal damage during the onset and progression of DR. Alpha kinase 1 (ALPK1), a member of a recently discovered serine/threonine...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Ting Wu, Yin-Kun Guo, Fang-Yi Long, Shang-Shang Duan, Xiao-Hong Li, Guo Liu, Jun-Rong Du, Nai-Hong Yan
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Subjects:	ALPK1 diabetic retinopathy Db/db diabetic mice Pyroptosis
Online Access:	https://doi.org/10.1038/s41598-025-17122-x