Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys.

Parkinson's disease presents nonmotor complications such as autonomic dysfunction that do not respond to traditional anti-parkinsonian therapies. The lack of established preclinical monkey models of Parkinson's disease with cardiac dysfunction hampers development and testing of new treatme...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Valerie Joers, Kailie Seneczko, Nichole C Goecks, Timothy J Kamp, Timothy A Hacker, Kevin G Brunner, Jonathan W Engle, Todd E Barnhart, R Jerome Nickles, James E Holden, Marina E Emborg
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3335153?pdf=render