Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies

Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes that negatively regulate the immune response to cancer and chronic infections. Abnormal myelopoiesis and pathological activation of myeloid cells generate this heterogeneous population of myeloid-derived...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Vaishali Bhardwaj, Stephen M. Ansell
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Subjects:	myeloid-derived suppressor cells hematological malignancies tumor microenvironment t cells immunosuppression
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1129343/full