ErbB polymorphisms: Insights and implications for response to targeted cancer therapeutics

Advances in high-throughput genomic-scanning have expanded the repertory of genetic variations in DNA sequences encoding ErbB tyrosine kinase receptors in humans, including single nucleotide polymorphisms (SNPs), polymorphic repetitive elements, microsatellite variations, small-scale insertions and...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Moulay A Alaoui-Jamali, Gregoire Bernard Rene Morand, Sabrina Daniela Silva
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-02-01
Subjects:	Cancer snps ErbB receptors anti-ErbB therapeutic drug response and resistance
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00017/full