SETD2 in MLL-rearranged leukemia – a complex case

Oncogenic MLL-fusion proteins often hijack essential molecular mechanisms during leukemogenesis. The histone methyltransferase SETD2 was implicated in the regulation of transcription, DNA damage and other cellular processes. Recent studies identified a critical role for SETD2 in MLL-rearranged leuke...

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Bibliographic Details
Published in:Molecular & Cellular Oncology
Main Authors: Anna Skucha, Jessica Ebner, Florian Grebien
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2018.1503492