Thrombomodulin-modified thrombin generation after in vivo recombinant factor VIII treatment in severe hemophilia A

Background Thrombin generation has been shown to reflect coagulation potential and factor VIII (FVIII) levels in patients with hemophilia A. We hypothesize that thrombin generation in the presence of thrombomodulin reflects plasma FVIII levels better.Design and Methods Plasma FVIII levels were deter...

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Bibliographic Details
Published in:Haematologica
Main Authors: Arne W.J.H. Dielis, Wolfgang M.R. Balliël, René van Oerle, Wim T. Hermens, Henri M.H. Spronk, Hugo ten Cate, Karly Hamulyák
Format: Article
Language:English
Published: Ferrata Storti Foundation 2008-09-01
Online Access:https://haematologica.org/article/view/4994