YAP promotes the early development of temporomandibular joint bony ankylosis by regulating mesenchymal stem cell function

Abstract To explore the role of YAP, a key effector of the Hippo pathway, in temporomandibular joint (TMJ) ankylosis. The temporal and spatial expression of YAP was detected via immunohistochemistry and multiplex immunohistochemistry on postoperative Days 1, 4, 7, 9, 11, 14 and 28 in a sheep model....

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Tong-Mei Zhang, Mai-Ning Jiao, Kun Yang, Hua-Lun Wang, Chang-Song Zhang, Shi-Hua Wang, Guan-Meng Zhang, He-Jing Miao, Jun Shen, Ying-Bin Yan
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Subjects:
Temporomandibular joint ankylosis
Hippo/YAP
ShRNA
Trauma
Osteogenic
Sheep
Online Access:https://doi.org/10.1038/s41598-024-63613-8

Internet

https://doi.org/10.1038/s41598-024-63613-8

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