Histone Methyltransferase EZH2: A Potential Therapeutic Target for Kidney Diseases
Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme that catalyzes the addition of methyl groups to histone H3 at lysine 27, leading to gene silencing. Mutation or over-expression of EZH2 has been linked to many cancers including renal carcinoma. Recent studies have sho...
| 發表在: | Frontiers in Physiology |
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| Main Authors: | , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Frontiers Media S.A.
2021-02-01
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| 主題: | |
| 在線閱讀: | https://www.frontiersin.org/articles/10.3389/fphys.2021.640700/full |