ZC3H12A: A Critical Mediator of Inflammation, Tumor Immunotherapy, and Metabolic–Immune Crosstalk—Implications for Disease Treatment

ZC3H12A is a key RNA-binding protein and ribonuclease that plays a central role in negatively regulating inflammation and maintaining immune homeostasis. It does this by degrading the mRNA of multiple inflammatory mediators (such as <i>IL-6</i> and <i>IL-1β</i>), as well as t...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Mingjun Lu, Jingwei Guo, Chenyang Wang, Bingbing Wan, Teng Ma
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	ZC3H12A ribonuclease inflammation tumor immunotherapy CAR-T
Online Access:	https://www.mdpi.com/2218-273X/15/10/1473