In vitro skin penetration of clobetasol from lipid nanoparticles: drug extraction and quantitation in different skin layers

Clobetasol propionate (CP) is a potent topical corticosteroid that causes several cutaneous and systemic side effects. In the present work, CP was encapsulated in nanostructured lipid carriers (NLCs) to increase drug retention in the outer skin layers and improve the safety of topical therapy. NLCs...

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Bibliographic Details

Published in:	Brazilian Journal of Pharmaceutical Sciences
Main Authors:	Luís Antônio Dantas Silva, Stephânia Fleury Taveira, Eliana Martins Lima, Ricardo Neves Marreto
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2012-12-01
Subjects:	Proprionato de clobetasol Carreadores lipídicos nanoestruturados Clobetasol propionate Nanostructured lipid carriers
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000400025