Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies

Allergic (Th2high immunophenotype) asthmatics have a heightened susceptibility to common respiratory viral infections such as human rhinovirus. Evidence suggests that the innate interferon response is deficient in asthmatic/atopic individuals, while other studies show no differences in antiviral res...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jean-François Lauzon-Joset, Anya C. Jones, Kyle T. Mincham, Jenny A. Thomas, Louis A. Rosenthal, Anthony Bosco, Patrick G. Holt, Deborah H. Strickland
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-08-01
Subjects:	rhinovirus Th2-atopy type I interferon allergic asthma microarray
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01805/full