Hippo signaling pathway regulates Ebola virus transcription and egress

Abstract Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress. Specifically, we find that when YAP is phosphorylated by LATS1/2, i...

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出版年:	Nature Communications
主要な著者:	Jingjing Liang, Marija A. Djurkovic, Carson G. Leavitt, Olena Shtanko, Ronald N. Harty
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2024-08-01
オンライン･アクセス:	https://doi.org/10.1038/s41467-024-51356-z