In silico prediction of nonpermissive HLA-DPB1 mismatches in unrelated HCT by functional distance

Abstract: In silico prediction of high-risk donor–recipient HLA mismatches after unrelated donor (UD) hematopoietic cell transplantation (HCT) is an attractive, yet elusive, objective. Nonpermissive T-cell epitope (TCE) group mismatches were defined by alloreactive T-cell cross-reactivity for 52/80...

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Bibliographic Details
Published in:Blood Advances
Main Authors: Esteban Arrieta-Bolaños, Pietro Crivello, Bronwen E. Shaw, Kwang Woo Ahn, Hai-Lin Wang, Michael R. Verneris, Katharine C. Hsu, Joseph Pidala, Stephanie J. Lee, Katharina Fleischhauer, Stephen R. Spellman
Format: Article
Language:English
Published: Elsevier 2018-07-01
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920309320