Triptolide-mediated immunomodulation of macrophages: from pathophysiology to therapy

Background Triptolide (TP), a potent bioactive compound from the Chinese herb Tripterygium wilfordii, demonstrates strong anti-inflammatory and immunosuppressive effects. Evidence indicates that TP modulates macrophage polarization and regulates inflammatory responses through multiple signaling path...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	Yi Chen, Qiuyu Zhu, Ankang Yin, Wei Wang, Juan Wang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Triptolide macrophage immunomodulation molecular target
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2025.2575302