Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells

Our study assesses the effects of anti-VEGF (Vascular Endothelial Growth Factor) drugs and Trichostatin A (TSA), an inhibitor of histone deacetylase (HDAC) activity, on cultured ARPE-19 (Adult Retinal Pigment Epithelial-19) cells that are immortalized human retinal pigment epithelial cells. ARPE-19...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Mohamed A. Hamid, M. Tarek Moustafa, Sonali Nashine, Rodrigo Donato Costa, Kevin Schneider, Shari R. Atilano, Baruch D. Kuppermann, M. Cristina Kenney
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	AMD age-related macular degeneration trichostatin A (TSA) HDAC histone deacetylase vascular endothelial growth factor (VEGF)
Online Access:	https://www.mdpi.com/2073-4409/10/4/878