Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies

Monoclonal antibodies have become an important class of therapeutics in the last 30 years. Because the mechanism of action of therapeutic antibodies is intimately linked to their binding epitopes, identification of the epitope of an antibody to the antigen plays a central role during antibody drug d...

詳細記述

書誌詳細

出版年:	mAbs
主要な著者:	Xibei Dang, Lars Guelen, David Lutje Hulsik, Grigori Ermakov, Edward J. Hsieh, Joost Kreijtz, Judith Stammen-Vogelzangs, Imke Lodewijks, Astrid Bertens, Arne Bramer, Marco Guadagnoli, Alexis Nazabal, Andrea van Elsas, Thierry Fischmann, Veronica Juan, Amy Beebe, Maribel Beaumont, Hans van Eenennaam
フォーマット:	論文
言語:	英語
出版事項:	Taylor & Francis Group 2023-12-01
主題:	Alanine scan cross-linking Epitope mapping Hydrogen deuterium exchange hydroxyl radical footprinting monoclonal antibodies
オンライン･アクセス:	https://www.tandfonline.com/doi/10.1080/19420862.2023.2285285