Amyloidogenic light chains impair plasma cell survival

Systemic light chain amyloidosis (AL) is a clonal plasma cell disorder characterized by the deposition of misfolded immunoglobulin light chains (LC) as insoluble fibrils in organs. The lack of suitable models has hindered the investigation of the disease mechanisms. Our aim was to establish AL LC-p...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Haematologica
المؤلفون الرئيسيون: Marjorie Pick, Eyal Lebel, Sharona Elgavish, Hadar Benyamini, Yuval Nevo, Rachel Hertz, Jacob Bar-Tana, Paola Rognoni, Giampaolo Merlini, Moshe E. Gatt
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Ferrata Storti Foundation 2023-06-01
الوصول للمادة أونلاين:https://haematologica.org/article/view/11135