Identification of passive wrist-worn accelerometry outcomes for improved disease monitoring and trial design in motor neuron diseaseResearch in context

Summary: Background: Motor neuron disease (MND) leads to progressive functional decline, making reliable measures of disease progression critical for patient care and clinical trials. Current clinical outcome measures lack the ability to continuously and objectively track functional decline in dail...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Cory J. Holdom, Rakesh Pilkar, Christine C. Guo, Ruben P.A van Eijk, Nadia Sethi, Robert D. Henderson, Shyuan T. Ngo, Frederik J. Steyn
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Subjects:	Amyotrophic lateral sclerosis Clinical outcome measures Actigraphy Remote monitoring
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396425002233