A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

Background Preclinical studies have shown synergy between radiation therapy and immunotherapy. However, in almost all preclinical models, radiation is delivered in single doses or short courses of high doses (hypofractionated radiation). By contrast in most clinical settings, radiation is delivered...

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Bibliographic Details

Published in:	Journal for ImmunoTherapy of Cancer
Main Authors:	Benjamin Cottam, Kristina Young, Pippa Newell, Todd Crocenzi, Chet Hammill, Zeljka Jutric, Ronald F. Wolf, Paul D. Hansen, Matthew C. Solhjem, Yue-Yun To, Amy Greathouse, Garth Tormoen, Keith S. Bahjat, Michael J. Gough, Marka R. Crittenden
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2016-11-01
Online Access:	https://jitc.bmj.com/content/4/1/45.full