Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation.
The nick translation property of DNA polymerase I (Pol I) ensures the maturation of Okazaki fragments by removing primer RNAs and facilitating ligation. However, prolonged nick translation traversing downstream DNA is an energy wasting futile process, as Pol I simultaneously polymerizes and depolyme...
| 出版年: | PLoS ONE |
|---|---|
| 主要な著者: | , , , |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
Public Library of Science (PLoS)
2018-01-01
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| オンライン･アクセス: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199559&type=printable |