Associations among HPV persistence, the vaginal microbiome, and cervical cancer recurrence

Abstract Background In the US, up to 60% of cervical cancer (CxCa) survivors will have persistent HPV infection, the causative agent of CxCa, and up to 35% will develop recurrent local CxCa within 4 years after chemo-radiation therapy. Preliminary studies suggest healthy vaginal microbiome (VM) coul...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Despina Tsementzi, Rebecca Meador, Tony Eng, Joseph Shelton, Isabelle Scott, Konstantinos T. Konstantinidis, Susan Modesitt, Deborah Watkins Bruner
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Online Access:	https://doi.org/10.1186/s12967-025-06811-w