Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer
Summary: Cancer cells overexpress a diversity of anti-apoptotic BCL-2 family proteins, such as BCL-2, MCL-1, and BFL-1/A1, to enforce cellular immortality. Thus, intensive drug development efforts have focused on targeting this class of oncogenic proteins to overcome treatment resistance. Whereas a...
| الحاوية / القاعدة: | Cell Reports |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Elsevier
2018-09-01
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| الوصول للمادة أونلاين: | http://www.sciencedirect.com/science/article/pii/S2211124718314086 |
