Regulation of hematopoietic stem cells differentiation, self-renewal, and quiescence through the mTOR signaling pathway

Hematopoietic stem cells (HSCs) are important for the hematopoietic system because they can self-renew to increase their number and differentiate into all the blood cells. At a steady state, most of the HSCs remain in quiescence to preserve their capacities and protect themselves from damage and exh...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Bai Ling, Yunyang Xu, Siyuan Qian, Ze Xiang, Shihai Xuan, Jian Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	hematopoietic stem cells (HSCS) mTOR differentiation self-renewal quiescence
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1186850/full