The BDNF val-66-met Polymorphism Affects Neuronal Morphology and Synaptic Transmission in Cultured Hippocampal Neurons from Rett Syndrome Mice

Brain-derived neurotrophic factor (Bdnf) has been implicated in several neurological disorders including Rett syndrome (RTT), an X-linked neurodevelopmental disorder caused by loss-of-function mutations in the transcriptional modulator methyl-CpG-binding protein 2 (MECP2). The human BDNF gene has a...

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書誌詳細

出版年:	Frontiers in Cellular Neuroscience
主要な著者:	Xin Xu, Jordi Garcia, Rachel Ewalt, Shelly Nason, Lucas Pozzo-Miller
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2017-07-01
主題:	BDNF val66met Rett syndrome dendritic branching dendritic spines synaptic transmission
オンライン･アクセス:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00203/full