Synthesis and biological study of novel FELL analogs containing L- or d-tyr instead of l-phe in the N-terminus

The high prevalence of pain affecting millions of people worldwide made it a major health problem. At the same time often, inflammation is closely associated to the pain. Thus, creation of molecules with a double effect is a good alternative to the currently existing in the medicinal practice non-st...

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Bibliographic Details

Published in:	Current Research in Biotechnology
Main Authors:	Boryana Borisova, Hristina Nocheva, Hristina Zlatanova-Tenisheva, Marie Laronze-Cochard, Stéphane Gérard, Dancho Danalev
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	FELL analogs Analgesic activity Paw-pressure test Anti-inflammatory activity Carrageenan-induced paw edema test
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590262825000632