Validation of Sputum Biomarker Immunoassays and Cytokine Expression Profiles in COPD

Immunoassays are commonly used to assess airway inflammation in sputum samples from chronic obstructive pulmonary disease (COPD) patients. However, assay performance and validation in this complex matrix is inconsistently reported. The aim of this study was to assess the suitability of various immun...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Alex Mulvanny, Caroline Pattwell, Augusta Beech, Thomas Southworth, Dave Singh
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Subjects:
chronic obstructive pulmonary disease
validation
biomarker
sputum
inflammatory endotype
airway colonisation
Online Access:https://www.mdpi.com/2227-9059/10/8/1949

Internet

https://www.mdpi.com/2227-9059/10/8/1949

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