Mitophagy in Doxorubicin-Induced Cardiotoxicity: Insights into Molecular Biology and Novel Therapeutic Strategies

Doxorubicin is a chemotherapeutic drug utilized for solid tumors and hematologic malignancies, but its clinical application is hampered by life-threatening cardiotoxicity, including cardiac dilation and heart failure. Mitophagy, a cargo-specific form of autophagy, is specifically used to eliminate d...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Heng Zhang, Saiyang Xie, Wei Deng
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Subjects:	doxorubicin cardiotoxicity mitochondria mitophagy treatment
Online Access:	https://www.mdpi.com/2218-273X/14/12/1614