Long non-coding RNA CDKN2B-AS1 regulates high glucose-induced human mesangial cell injury via regulating the miR-15b-5p/WNT2B axis

Abstract Background Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) has been reported to be related to diabetic nephropathy (DN) progression. However, the regulatory mechanisms of CDKN2B-AS1 in DN are unclear. Methods High glucose (HG) was used to induce human m...

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Bibliographic Details
Published in:Diabetology & Metabolic Syndrome
Main Authors: Jing Chang, Yanming Yu, Zhan Fang, Haiyan He, Dan Wang, Jian Teng, Lina Yang
Format: Article
Language:English
Published: BMC 2020-12-01
Subjects:
Online Access:https://doi.org/10.1186/s13098-020-00618-z