Self-Renewal of Macrophages: Tumor-Released Factors and Signaling Pathways

Macrophages are the most abundant immune cells of the tumor microenvironment (TME) and have multiple important functions in cancer. During tumor growth, both tissue-resident macrophages and newly recruited monocyte-derived macrophages can give rise to tumor-associated macrophages (TAMs), which have...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Serena Filiberti, Mariapia Russo, Silvia Lonardi, Mattia Bugatti, William Vermi, Cathy Tournier, Emanuele Giurisato
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	tumor-associated macrophages self-renewal metabolic signature signaling pathways proliferation
Online Access:	https://www.mdpi.com/2227-9059/10/11/2709