Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Claire Dutson, Esther Allen, Mark J. Thompson, Joseph H. Hedley, Heather E. Murton, David M. Williams
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	C5-modified dNTPs polyanionic reporter group DNA polymerases
Online Access:	https://www.mdpi.com/1420-3049/26/8/2250