Translational toxicoepigenetic Meta-Analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead exposure in mouse and human offspring

Although toxicology uses animal models to represent real-world human health scenarios, a critical translational gap between laboratory-based studies and epidemiology remains. In this study, we aimed to understand the toxicoepigenetic effects on DNA methylation after developmental exposure to two com...

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Bibliographic Details

Published in:	Environment International
Main Authors:	Rebekah L. Petroff, Dana C. Dolinoy, Kai Wang, Luke Montrose, Vasantha Padmanabhan, Karen E. Peterson, Douglas M. Ruden, Maureen A. Sartor, Laurie K. Svoboda, Martha M. Téllez-Rojo, Jaclyn M. Goodrich
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Subjects:	DNA methylation DEHP Lead (Pb) Developmental exposures Translational toxicology Epigenetics
Online Access:	http://www.sciencedirect.com/science/article/pii/S0160412024001612